Adaptimmune’s Collaboration with Genentech

Ropes & Gray represented Adaptimmune in the deal.

Adaptimmune signed its strategic collaboration with Roche Group’s Genentech Inc. to research, develop and commercialize cancer-target allogeneic T-cell therapies, under which the companies will combine their technologies and expertise to research and develop “off-the-shelf” cell therapies for up to five cancer targets and develop a novel allogeneic personalized cell therapy platform.

Under the terms of the agreement, Adaptimmune will receive $150 million upfront, $150 million over the next five years in additional payments, and development, regulatory and commercial milestones payments potentially exceeding $3 billion in aggregate value, as well as royalties, across multiple programs. Adaptimmune also has a right to opt in to a 50/50 U.S. profit/cost share on “off-the-shelf” products. If Adaptimmune elects to opt in, then it will be eligible to share 50 percent of profits and losses from U.S. sales on such products and is eligible to receive ex-U.S. regulatory and sales-based milestone payments, as well as royalties on ex-U.S. net sales. Adaptimmune also has a right to co-promote products for which it has opted in in the U.S.

Adaptimmune is a clinical-stage biopharmaceutical company focused on the development of novel cancer immunotherapy products for people with cancer. The Company’s unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors. 

Genentech, Inc., is an American biotechnology corporation which became a subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within Roche.

The Ropes & Gray team was led by IP transactions partner David McIntosh (Picture) and IP transactions associates Evan Tallmadge (both of Boston) and Sonya Aggarwal (San Francisco) and included IP transactions partner Hannah England (Freeman) (Boston), antitrust partners Mike McFalls (Washington, D.C.) and Ruchit Patel (London), litigation & enforcement counsel Deidre Johnson and associate Derek Yee (both of Boston).

Involved fees earner: Sonya Aggarwal – Ropes & Gray; Hannah England – Ropes & Gray; Deidre Johnson – Ropes & Gray; Michael McFalls – Ropes & Gray; David McIntosh – Ropes & Gray; Ruchit Patel – Ropes & Gray; Evan Tallmadge – Ropes & Gray; Derek Yee – Ropes & Gray;

Law Firms: Ropes & Gray;

Clients: Adaptimmune;

Author: Martina Bellini